ANSWER
Articles that update the state of knowledge about osteoporosis risk becoming out of date quickly because research and studies on the disease are currently piqueing the interest of researchers, the pharmaceutical and medical equipment industries, governments, and even WHO. Osteoporosis is well-known among orthopedists due to its most serious complication: osteoporotic fracture. Because osteoporosis without fractures is a pathological condition with a nonspecific clinical profile, it is not cause for concern.
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Osteoporotic fractures have an economic (treatment) cost, a social (consequences) cost, and a medical cost (from deaths). Many fractures could be avoided if osteoporosis was diagnosed prior to the first fracture, resulting in many temporary and permanent disabilities and many lives saved. Awareness of osteoporosis risk factors raises suspicions, and bone densitometry aids in diagnosis. The physiopathology of the disease should be used to guide treatment. As a result, in order to prevent or treat osteoporosis, the activity of osteoclasts should be reduced, or the activity of osteoblasts should be increased, or both.
Treatment that reduces fracture occurrence by improving bone geometry and microarchitecture would be ideal. Good cell and matrix quality, normal mineralization, a good ratio of mineralized (mechanically resistant) to non-mineralized (flexible) bone, and no accumulated damage are all requirements for newly formed bone tissue. The ideal treatment should have a high remodeling rate as well as immediate and long-lasting therapeutic effects. These effects must be easily detectable. They must be safe.
QUESTION
Answer the following questions in your own words, remaining objective and concise while remaining professional. 1. You are reviewing four women with osteoporosis risk factors during a case presentation at your clinic. Which patient is least likely to have osteoporosis? A. Nehineza is an obese African American woman with a family history of uterine cancer. B. Cristina is a Hispanic woman who leads a sedentary lifestyle C. Park-Gim-Ka, an underweight Asian woman with a tobacco use history D. Skylar is a Caucasian woman who is going through menopause. 2.. Densitometry results are given as T-scores; which values indicate osteopenia? 3. Following a thorough examination of your patient, you decide to begin osteoporosis treatment. Which class of medication is considered first-line therapy? Are there any things to think about before beginning therapy? What recommendations would you make to the patient about this treatment?