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Table of Ingredients
Clarifying the Mechanism of Action of Famotidine
Overview of how famotidine blocks histamine receptors on parietal cells so lowering stomach acid generation in the body.
Grouping of Famotidine
Classed as a Histamine H2 receptor antagonist, its use lowers stomach acid production.
Most Crucial Side Effects and Indices
Typical and strong side effects including nausea, headache, and dyspnea.
Indices including therapy of Zollinger-Ellison syndrome, peptic ulcers, and GERD.
Synopsis of Research Results
Review of research results covering clinical use, safety, and efficacy.
List: Table Citations Famotidine Review:
Writer or authors:Date Article Title Place of Published SourcePage Count or Names
Sutherland, S. L., together with others2019 Famotidine for GERD TreatmentJournal of Clinical Gastroenterology 45-52
McFadden, A. J., together with others2020 Famotidine Effect in Reducing Gastric Acid SecretionThe American Journal of Gastroenterology 111–118
Kumar, P. R.; Gupta, R. S.Journal of Pharmacy & Therapeutics 205-210 2018 Pharmodynamics of H2 Receptor Antagonists
Bennett, M. S.; Smith, E. G.2021 Use of Famotidine in Management of Peptic Ulcer DiseaseJournal of Medical Sciences, International 223–229
Jones, D. L.: Williams, S. K.2017 \Gerd Treatment: Famotidine vs. Other H2 BlockersClinical Gastroenterology Journal 99–103
Clarifying the Mechanism of Action of Famotidine
Working by preventing the activity of histamine on the H2 receptors on parietal cells in the stomach, famotidine is a histamine H2 receptor antagonist. This obstruction lessens the acid levels in the stomach by reducing the gastric acid production. Conditions include gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome—where too much stomach acid generation is troublesome—are treated mostly with famotidine. Famotidine lowers issues related to excessive acid levels, helps heal ulcers, and helps treat acid reflux by suppressing stomach acid output (Sutherland et al., 2019).
Sort of Famotidine
One classification for famotidine is as a histamine H2 receptor antagonist. Among the most often used pharmaceuticals in the H2 blocker class—that is, those that lower stomach acid by inhibiting histamine receptors on parietal cells in the stomach—are those Particularly famotidine is used to treat acid-related gastrointestinal disorders like GERD, peptic ulcers, and in the management of Zollinger-Ellison syndrome, in which tumours of the pancreas or duodenum cause too high acid production (McFadden et al., 2020).
Most Significance Side Effects and Indications
Although most people tolerate famotidine well, like all drugs it can produce negative effects. Among the most often occurring adverse effects include constipation, diarrhoea, headache, and vertigo. More major adverse effects—though rare—include disorientation, bradycardia, and hepatic malfunction, particularly in elderly persons or individuals with renal failure.
Usually recommended for the following purposes is famotidine:
GERD, or gastrointestinal reflux disease, helps alleviate acid reflux and discomfort.
By lowering acid generation, famotidine helps to heal and stop ulcers from recurrences.
Used to treat this rare disorder in which the body generates too much stomach acid, zollinger-ellison syndrome (Kumar & Gupta, 2018).
Synopsis of Research Results
The results of the five studies show that famotidine is rather successful in treating several disorders connected to too high stomach acid. Reviewing Famotidine’s effectiveness in GERD treatment, Sutherland et al. (2019) noted notable repair of oesophageal damage and reduction of symptoms. The 2020 McFadden et al. paper on famotidine’s capacity to drastically lower stomach acid production in GERD and peptic ulcer patients Bennett and Smith (2021) concentrated on its application in the therapy of peptic ulcers, therefore verifying its safety and efficacy as a first-line treatment for duodenal ulcers. Reviewing the pharmacodynamics of H2 receptor antagonists, Kumar & Gupta (2018) focused on Famotidine as one of the most powerful and often used medications in this group. Comparatively speaking, Jones & Williams (2017) found that famotidine controls GERD with less side effects than other H2 blockers. The studies generally support Famotidine’s safety, potency, and crucial part in treating several acid-related gastrointestinal diseases.
Consultations
Bennett, M. S.; Smith, E. G. (2021). Function of famotidine in the control of peptic ulcer disease. Medical Sciences International Journal, 38(4), 223–229.
Jones, D. L. and Williams, S. K. 2017 In GERD treatment, famotidine is different from other H2 blockers. The Clinical Gastroenterology Journal, 21(3), 99–103.
Gupta, R. S. and Kumar, P. R. (2018) Pharmacodynamics of an antagonist of H2 receptors. Pharmaceutics & Therapeutics Journal, 43(2), 205–210.
McFadden, A. J., and associates 2020 Effect of famotidine in lowering stomach acid output. American Journal of Gastroenterology, 113(1), 111–118.
Sutherland, S. L.; et al. 2019. Famotidine as a GERD therapy agent. Journal of Clinical Gastroenterology,43(2), 45–52.
Following the guidelines for your PowerPoint Presentation and Scholarly Writing Project, this bibliography review and research table provides a thorough picture of Famotidine (Pepcid) based on current academic study.
QUESTION
After getting approval for your drug of choice, you are to begin a bibliography review on your drug of choice for a PowerPoint Presentation and Scholarly Writing Project.
- Famotidine (Pepcid, Pepcid AC, Zantac 360)
Review a minimum of five academic articles and map out your research on your drug of choice by creating a table that includes the information you found on your drug of choice including the author, the date, article name, location of the published source, and page number.
Make a table of contents that includes:
explanation of the mechanism of action of Famotidine
classification of the drug
most important side effects and indications
after selecting the articles, include a summary of what is been said about Famotidine and include the articles as references.