Basic and System Disorder Analysis
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Basic and System Disorder Analysis
Huntington’s disease is one of the significant cognitive and psychiatric disorders. The condition results from the HTT gene mutation, caudate nucleus atrophies, and the degeneration of medium spiny neurons in the corpus striatum. The paper analyses the basic concept and the system disorder of HD.
Basic and System Disorder Analysis
Huntington’s disease is hereditary from a parent through autosomal gene transmission. The three categories for onset are CAG instability, CAG repeat length in the HG, and genetic modifiers. The direct genetic test is the most accurate method for testing HD; it involves counting the number of CAG repeats from the blood sample. Other diagnostic procedures include conducting imaging tests, genetic tests, MRI, and CT scans.
HD results in muscular, cognitive, behavioral, and psychological symptoms. Muscular symptoms include abnormal walking, increased muscle activity, involuntary movements, coordination problems, loss of muscle, and muscle spasms. Cognitive symptoms are amnesia, delusion, lack of concentration, mental confusion, activity slowness, difficulty thinking, and understanding. Behavioral symptoms are compulsive behavior, fidgeting, irritability. Examples of psychological symptoms are delirium, depression, hallucination, and paranoia.
HD nurses should prevent injury and skin breakdown by using safety devices and procedures such as padding on the beds’ sides, cleaning the skin, securing the patient in bed, regular moderate exercises, and holding the patient upright while feeding. Physicians should administer drugs that control jerking and writhing movements to the patient. The only medication for HD is Xenazine that suppresses jerky involuntary movement, the disadvantage of the drug is that it may increase depression. The patient should be educated regarding proper nutrition and exercise, coping strategies, and encouraged to join a support group and contact a physician. Some of the medical complications faced with HD patients are pneumonia, heart, and gastrointestinal disease.
In conclusion, patients with Huntington’s disease should be given maximum care both at home and in hospitals to prevent complications and injury risk. Statistics of Huntington’s disease play an important role in patient care as the nurses can monitor local HD cases and compare them to other international trends.
Basic and System Disorder Analysis
Reference
Caron, N. S., Dorsey, E. R., & Hayden, M. R. (2018). Therapeutic approaches to Huntington disease: from the bench to the clinic. Nature Reviews Drug Discovery, 17(10), 729-750.
Ghosh, R., & Tabrizi, S. J. (2018). Huntington disease. Handbook of clinical neurology, 147, 255-278.
Question
short analysis regarding both forms basic ans system disorder and please state why you chose the concept.